PhotoSonus

Mobile High Energy Tunable Wavelength Laser System for Photoacoustic Imaging
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  • High output energy for larger area illumination
  • Pump laser, OPO and PSU in a single mobile unit
  • High 180 mJ output energy
  • Fast wavelength tuning available
  • High output energy for larger area illumination
  • Pump laser, OPO and PSU in a single mobile unit
  • High 180 mJ output energy
  • Fast wavelength tuning available

Features & Options

Features

  • High 180 mJ output energy
  • Wide tuning range from 660 to 1064 nm and from 1065 to 2300 nm
  • 10 Hz or 20 Hz pulse repetition rate
  • Integrated pump laser, OPO and PSU in single portable unit
  • One year warranty
  • Low maintenance cost
  • Fiber bundle connectors with safety interlock

Options

  • Fast wavelength tuning
  • High energy (250 mJ) – inquire separately
  • Motorized switching between OPO and pump wavelengths
  • Access to pump laser wavelengths (1064 / 532 nm)
  • Idler output 1065 – 2300 nm
  • Motorized attenuator
  • Energy meter
  • Fiber bundle

Description

Following the demand of high output energies in the photoacoustic market for imaging larger volumes of tissue, PhotoSonus, an updated high energy tunable laser source for photo-acoustic imaging is introduced. Time-tested Ekspla nanosecond pump laser, parametric oscillator, power supply and cooling unit are integrated in a single robust housing to provide mobility, ease of use and low maintenance cost.

Highly flexible PhotoSonus platform makes it easy to be integrated and used in a photoacoustic imaging system: it is fully motorized and computer controlled, have user trigger outputs / inputs and special options such as motorized switching between OPO and pump wavelengths.

Parametric oscillator generates output energies up to 180 mJ at peak of wide wavelength tuning range (660 – 2300 nm). Customizable and interlocked fiber bundle connector ensures safety and ability to fit various size fiber bundles.

For customers who demand even higher output energy, we are introducing PhotoSonus with High Energy option. 250 mJ output energy is achieved at the peak from OPO at 10 Hz. For more details inquire separately.

Specifications

MODEL 1)PhotoSonus
OPO
Wavelength range
    Signal660 – 1064 nm
    Idler (optional)1065 – 2300 nm
Pulse repetition range10 or 20 Hz
OPO output pulse energy 2)>180 mJ at 10 Hz or
>160 mJ at 20 Hz
Scanning step:
    Signal (660  – 1064 nm) 0.1 nm
    Idler (1065 –  2300 nm) 1 nm
Pulse duration 3)3 – 5 ns
Signal linewidth<10 cm-1
Typical signal beam diameter (1/e²) 4)7 ± 2 mm
Control interfacesUSB, LAN, RS232
PHYSICAL CHARACTERISTICS
CoolingClosed loop air-water cooled
Unit size (W × L × H)434 × 672 × 887 mm
OPERATING REQUIREMENTS
Room temperature18 – 27 °C
Relative humidity20 – 80 % (non-condensing)
Power requirements 5)208 or 240 VAC, single phase 50/60 Hz
Power consumption<1.8 kW at 10 Hz,
<3.4 kW at 20 Hz
  1. Due to continuous improvement, all specifications are subject to change without notice. The parameters marked typical are not specifications. They are indications of typical performance and will vary with each unit we manufacture. Unless stated otherwise all specifications are measured at 700 nm.
  2. Free space measurement at 700 nm. See tuning curves for typical outputs at other wavelengths.
  3. FWHM measured with photodiode featuring 500 ps rise time and 600 MHz bandwidth oscilloscope.
  4. Measured at the output at 700 nm wavelength. Can be adjusted as per request.
  5. Mains voltage should be specified when ordering.

Performance & Drawings

Publications

Found total :
7 articles, 7 selected
Application selected :
All Applications
All Applications
Biomedical – applications focusing on the biology of human health and disease
Photoacoustic Imaging – biomedical imaging modality based on the photoacoustic effect

Image Enchancement Algorithm of Photoacoustic Tomography using Active Countour Filtering

Related applications:  Photoacoustic Imaging Biomedical

Authors:  P. Palaniappan, D. H. Shin, C. G. Song

The photoacoustic images are obtained from a custom developed linear array photoacoustic tomography system. The biological specimens are imitated by conducting phantom tests in order to retrieve a fully functional photoacoustic image. The acquired image undergoes the active region based contour filtering to remove the noise and accurately segment the object area for further processing. The universal vack projection method is used as the image reconstruction algorithm. The active contour filtering is analyzed by evaluating the signal to noise ratio and comparing it with the other filtering methods.

Published: 2016.   Source: World Academy of Science, Engineering and Technology International Journal of Computer and Information Engineering Vol:10, No:4, 2016

Detecting Rat’s Kidney Inflammation Using Real Time Photoacoustic Tomography

Related applications:  Photoacoustic Imaging Biomedical

Authors:  M. Y. Lee, D. H. Shin, S. H. Park, W.C. Ham, S.K. Ko, C. G. Song

Photoacoustic Tomography (PAT) is a promising medical imaging modality that combines optical imaging contrast with the spatial resolution of ultrasound imaging. It can also distinguish the changes in biological features. But, real-time PAT system should be confirmed due to photoacoustic effect for tissue. Thus, we have developed a real-time PAT system using a custom-developed data acquisition board and ultrasound linear probe. To evaluate performance of our system, phantom test was performed. As a result of those experiments, the system showed satisfactory performance and its usefulness has been confirmed. We monitored the degradation of inflammation which induced on the rat’s kidney using real-time PAT.

Published: 2017.   Source: World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering Vol:11, No:8, 2017

A Custom Developed Linear Array Photoacoustic Tomography for Noninvasive Medical Imaging

Related applications:  Photoacoustic Imaging Biomedical

Authors:  P. Palaniappan, D. H. Shin, S. H. Park, M. Y. Lee, B. Y. Kim, S. Y. Lee, S. K. Go, C. G. Song

A real-time photoacoustic tomography which is capable of imaging the changes in biological features of living subject is presented. A custom developed data acquisition board and linear array transducer is used in this photoacoustic system. A phantom test were carried out to evaluate performance of the system. The developed system showed a satisfactory performance and its usefulness were evaluated. The universal back projection algorithm is used for image reconstruction and the sensitivity is analyzed from the obtained photoacoustic images.

Published: 2016.   Source: Event: 2016 IEEE International Conference on Consumer Electronics-Asia (ICCE-Asia)

Photoacoustic signal detection using interferometric fiber-optic ultrasound transducers

Related applications:  Photoacoustic Imaging Biomedical

Authors:  A. D. Salas-Caridad, G. Martínez-Ponce, R. Martínez-Manuel

The cross-section of a metallic sample was photoacoustically imaged using a pulsed nanosecond laser as the excitation source and a fiber-optic hydrophone system to acquire the pressure signal. The ultrasound sensor was an extrinsic Fabry-Perot fiber-optic interferometer and the band-limited photodetected output signal was recorded in a digital oscilloscope. In order to reconstruct the image, a time set of ultrasound signals acquired in a circular scan around the sample were used to solve the time-reversal equations. It was observed that image contrast can be enhanced considering the deconvolution of the sensor frequency response from each measured pressure signal.

Published: 2017.   Source: Event: SPIE Optical Engineering + Applications, 2017, San Diego, California, United States

Hydrophones based on interferometric fiber-optic sensors with applications in photoacoustics

Related applications:  Photoacoustic Imaging Biomedical

Authors:  A. D. Salas-Caridad, B. Eng.

Biomedical imaging used for medical diagnosis constantly requires improvement in the characteristics for imaging devices. The sensing devices are one of the most important pieces to improve in order to get images with better quality. In this thesis, it is proposed the use of interferometric fiber-optic sensors (which offer the advantages inherent to optical fibers) as devices to detect pressure/acoustic signals generated by the photoacoustic effect. It is explored the capability of using fiber-optic interferometric hydrophones in order to determine the thickness of a material derived from the acoustic signal generated when a sample is illuminated. In addition, the analysis of photoacoustic signals generated by the excitation of nanoparticles of an anisotropic material as absorption centers. Finally, the cross-section of a metallic sample was photoacoustically imaged by acquiring the pressure signals generated.

Published: 2017.   Source: Master of Optomechatronics | Leon, Guanajuato, Mexico

Enhancement of objects in photoacoustic tomography using selective filtering

Related applications:  Photoacoustic Imaging Biomedical

Authors:  D. Shin, Y. Yang, C. G. Song

Here we developed a real-time photoacoustic tomography (PAT) imaging acquisition device based on the linear array transducer utilized on ultrasonic devices. Also, we produced a phantom including diverse contrast media and acquired PAT imaging as the light source wavelength was changing to see if the contrast media reacted. Indocyanine green showed the highest reaction around the 800-nm band, methylene blue demonstrated the same in the 750-nm band, and gold nanoparticle showed the same in the 700-nm band. However, in the case of superparamagnetic iron oxide, we observed not reaction within the wavelength bands used herein to obtain imaging. Moreover, we applied selective filtering to the acquired PAT imaging to remove noise from around and reinforce the object’s area. Consequentially, we could see the object area in the imaging was effectively detected and the image noise was removed.

Published: 2015.   Source: Bio-Medical Materials and Engineering 26 (2015) S1223–S1230

Hybrid Photoacoustic/Ultrasound tomograph for real time finger imaging

Related applications:  Photoacoustic Imaging Biomedical

Authors:  M. Oeri, W. Bost, N. Sénégond, S. Tretbar, M. Fournelle

We report a target-enclosing, hybrid tomograph with a total of 768 elements based on capacitive micromachined ultrasound transducer technology and providing fast, high-resolution 2-D/3-D photoacoustic and ultrasound tomography tailored to finger imaging.A freely programmable ultrasound beamforming platform sampling data at 80 MHz was developed to realize plane wave transmission under multiple angles. A multiplexing unit enables the connection and control of a large number of elements. Fast image reconstruction is provided by GPU processing. The tomograph is composed of four independent and fully automated movable arc-shaped transducers, allowing imaging of all three finger joints. The system benefits from photoacoustics, yielding high optical contrast and enabling visualization of finger vascularization, and ultrasound provides morphologic information on joints and surrounding tissue. A diode-pumped, Q-switched Nd:YAG laser and an optical parametric oscillator are used to broaden the spectrum of emitted wavelengths to provide multispectral imaging. Custom-made optical fiber bundles enable illumination of the region of interest in the plane of acoustic detection. Precision in positioning of the probe in motion is ensured by use of a motor-driven guide slide. The current position of the probe is encoded by the stage and used to relate ultrasound and photoacoustic signals to the corresponding region of interest of the suspicious finger joint. The system is characterized in phantoms and a healthy human finger in vivo. The results obtained promise to provide new opportunities in finger diagnostics and establish photoacoustic/ultrasoundtomography in medical routine.

Published: 2017.   Source: Ultrasound in Med. & Biol., 2017

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