Manufacturer of solid state lasers and systems for science and technology
29 May, 2020

Employing SFG spectroscopy in protein structure studies

Langmuir, the highly reputed ACS (American Chemical Society) magazine, in it’s May issue, published an interesting study called “Structure Determination of Hen Egg-White Lysozyme Aggregates Adsorbed to Lipid/Water and Air/Water Interfaces” which was featured on the magazine‘s cover. The picture in the cover art was made by the article co-authors and young perspective scientist Simona Strazdaitė a senior research fellow in the Department of Organic Chemistry at the Center for Physical Sciences and Technology (FTMC). The cover art illustrates the technique employed in the article – a surface-specific technique, vibrational sum-frequency generation spectroscopy. It was applied to study the structure of lysozyme aggregates adsorbed to a lipid monolayer.

These studies are very important in helping to understand how neurodegenerative diseases, like Alzheimer’s and Parkinson’s, are evolving.

Ekspla is proud that its customized version of the SFG spectrometer was employed in these important studies.

The article can be found here.